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home - Stomach - Gastric Polyps and Masses - Gastric Polyps Adenomas Written by Dr Sebastian Zeki

Gastric Polyps Adenomas

Gastric Adenomas (6.6%) PathologyAdenomas usually present in thr antrum, but can occur elsewhere.Polyps are flat or polypoid, from a few mm to several cm.Polyps are classified as intestinal or gastric type.They are similar to typical colonic adenomas.They are tubular, tubulovillous, or villous (papillary).They have dysplastic columnar cells with striated borders and with dysplastic goblet cells, Paneth cells, parietal cells, or endocrine cells.Polyps are associated with underlying chronic gastritis with intestinal metaplasia. Risk Factors for Malignant Transformation:Increasing size.Villous (papillary)- develop malignancy in 65 %.Higher grades of dysplasia.Non-flat adenomas. PathogenesisThis is the same as gastric adenocarcinoma.40% of adenomas are associated with synchro-nous gastric carcinomas.Progression risk of low grade adenoma is around 5% within 15 months- higher than colonic adeno-mas Tubular, tubulovillous, or villous (papillary) Clinical features of Gastric AdenomasThese usually on background of chronic gastritis.The incidence is the same in men and women.These occur in middle and older age subjects. Written by Dr Sebastian Zeki

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