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home - Stomach - Gastric Polyps and Masses - Gastric Polyps Written by Dr Sebastian Zeki

Gastric Polyps

Gastric Polyps Gastric polyps in cancer family syndromesFamilial adenomatous polyposis is associated with gastric or duodenal polyps in 40 -100 % of patients- usually non-neoplastic but gastric adenomas can occur.40 % of FAP associated fundic gland polyps are dysplastic- usually low-grade (PPI assoc fundic gland polyps usually benign).FAP need regular upper GI surveillance.Peutz-Jeghers syndrome get hamartomatous polyps in the stomach.The malignant potential is low of Peutz_Jegher’s related hamartomas is low. Management Indications for removal:The polyp is >2cm.The patient is symptomatic.The polyp is an adenoma.Biopsy or polypectomy is recommended when a polyp is encountered. Multiple PolypsBiopsy or excise the largest and send representative biopsies from others. Adenomatous gastric polyps (NiN) should be completely excisedMay warrant surveillance OGD Fundic Gland Polyps>1 cm in diameter should probably be removed If multiple, consider PPI withdrawalNo surveillance endoscopy needed Hyperplastic polypsHelicobacter eradication may cause regressionRemove if >1cm as risk of dysplasia Always search carefully for signs of gastric cancer if hyperplastic/ adenomas seenIf extensive atrophy (OLGA stage 3/4) OGD every 1-3 yearsIf OLGA 1-2 one further OGD Written by Dr Sebastian Zeki

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