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home - IBD - Treatment - Perianal Disease Written by Dr Sebastian Zeki

Knows the criteria for assessing the severity and extent of IBD, in
particular recognition of acute severe colitis. Knows treatment options
including aminosalicylates, corticosteroids, and steroid sparing

Knows differing methods of delivery for therapy.
Selects of appropriate treatment for extent and severity of disease,
including timing of immunomodulator therapy and referral for surgery.

Recognises the urgency of treating acutely sick patients, including
multidisciplinary team early, particularly surgeons. Clearly explains
the clinical situation and treatment options to patient and family.
Involves patient and family in decision making about treatment

Knows the complications of IBD including stricturing, fistulae,
extraintestinal manifestations, colon cancer and special situations
such as pregnancy.

Able to recognise potential complications and take appropriate action
to investigate and alter treatment as necessary including referral for
surgery and involvement of other healthcare professionals

Works with patient to explain complications and options for treatment
Involves the multidisciplinary team especially IBD nurse and surgeon
in management, and tailors treatment to the needs of the patient.
Discusses with colleagues early and appropriately



Understands the importance of multidisciplinary decision making
including when radiological histopathological and surgical opinions
should be sought

Understands the role of the IBD nurse within the MDT and in
communicating with patients and their relatives

Recognises the importance of other healthcare professionals in
providing high quality care including dieticians and pharmacists

Aware of the surgical options available in IBD and how to access

Has appropriate discussions with other specialties including
surgeons and other healthcare professionals

Can participate in an IBD MDT effectively
Relates well with all other healthcare professionals involved in IBD
patient care especially the IBD Nurse Specialist

Shows commitment to team-working and shows understanding of the
roles of other healthcare professionals with courtesy

Explains decision making process to the patient clearly and



Knows the different treatment modalities for IBD given the disease
extent activity previous history and complications

Knows the modes of delivery of different drug therapies and their
advantages and disadvantages

Recognises the importance of patient choice in deciding therapy and
in helping to ensure adherence

Understands when surgery is the most appropriate therapeutic option
and to make appropriate referrals

Demonstrates the ability to identify the possible range of appropriate
treatments for a particular patient and have an appropriate discussion
allowing the patient and doctors to come to a sensible consensus

Effectively communicates the possible treatment options and the
potential benefits complications and side effects of each



Knows the effect of active IBD drug therapy and surgery on fecundity
and pregnancy specifically issues relating to immune suppressants
biological therapy and surgery

Knows the effect of IBD and its treatment on breast feeding
Knows the effects of the disease and its treatment on the chances of
conception for men with IBD

Appreciates when to alter treatment to take account of pregnancy and
breast feeding

Can provide accurate advice about the effect of disease treatment
and surgery on fecundity pregnancy and lactation

Can discuss in an appropriate manner the treatment options for
patients wishing to conceive who are already pregnant or who wish
to breast feed

Explains the issues relating to treatment to those patients and their
partners who are planning to conceive so as to enable them to make
informed choices



Knows the risks relating to a previous history of malignancy or the
development of malignancy in IBD in particular to understand how
this affects treatment options

Knows the risks relating to infection with hepatitis B hepatitis C and
HIV connected with treatment of IBD

Knows the circumstances in which patients should be screened or
immunised for infectious diseases before commencing therapy

Can identify patients at risk for particular treatment due to concurrent
or pervious medical conditions

Can identify patients who need to be screened or immunised for
infectious diseases prior to therapy

Understands the treatment options available for patients with preexisting medical conditions

Can explain to patients the reasons for screening /immunising
Can explain the way that treatment may be affected by other medical
conditions and to start appropriate treatment

Perianal Disease

Perianal Crohns (occurs in 35%)Can precede intestinal disease by yearsMore common in colonic or IC disease Perianal FistulasOccur in 20% of CD overall.95% of colonic with rectal disease CD get fistulas.Fistula are usually secondary to penetrating abscesses. Anal Ulcers Anorectal Strictures and Stenosis43% will need panproctocolectomy.50% are in the rectum.30% are in the anus.These are associated with proctitis.50% also have abscesses.This can result from long term inflammation.Treat with gentle dilatation (Hegar-type).Maintenance therapy with a rectal steroid suspension given weekly is of benefit. Occur in 50%with perianal Crohn’s- usually related to anal fistulas. They recur in 50% in 2 years.Clin Pres: severe, constant anal pain/ worse on sitting/ defaecationFever and malaise if severePurulent rectal drainage may be notedO/E: Area of fluctuation or a patch of erythematous, indurated skin overlying the perianal or ischiorectal space is noted.May be no findingsTreatment: Drain the abscess cavity without damaging the anal sphincter.Involves local incision and drainage, catheter drainage, or seton placement. HaemorrhoidsDistinguish from hypertrophied skin tags that are associated with perianal Crohn's disease (tender and assoc with anal cancal ulceration.Treatment should be local and conservative.Avoid haemorrhoidectomy due to wound-healing and damage to anal sphincter. (26% get fistulas)Crohn’s fissure characteristics:1. Location other than the posterior midline (although most Crohn's fissures are in the post-rior midline)2. Multiple, recurrent or nonhealing fissures, 3. Fissures that are asymptomatic.4. Hypertrophic, edematous, and tender skin tags may be present which look like external hemor-rhoids, but are characteristic of Crohn's disease and may show granulomas if biopsied.TreatmentRelieve symptoms:Decrease fecal soilage by reducing diarrhea and local cleansing with sitz baths.Keep anoderm clean and dry, but without exces-sive wiping or use of astringent cleaners.Bathing following defecation is helpful, if possible.Alternatively, a premoistened pad or tissue can be used for wiping.Following bathing, the area should be dried using a soft towel with a dabbing motion, or with a hair drier.Treat Crohn’s with intestinal inflammationAntibiotics: Metronidazole/Combination wth ciprofloxacin may be usefulCombination with 5-ASA supp. is beneficial.Evidence for macrolides is anecdotal.Topical nitroglycerin- not useful for Crohn’s ulcera-tionHyperbaric oxygen- may be useful in refractory cases but only small trialsSurgery- if resistant to conservative treatment. Anorectal CarinomaRisk increased esp with long standing or stricturing disease.It can develop in fistulas. Anal Fissures And Ulcerations: Anorectal Abscesses Written by Dr Sebastian Zeki

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