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Extra Intestinal Manifestations -
Ocular
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Written by Dr Sebastian Zeki
MCQs for this page
Ocular
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Ocular manifestations
Episcleritis
This occurs in 2-5% of IBD.
It causes a painless (can get burning) hyperaemia .
Diagnose by s
lit lamp examination.
Treatment involves
treating the underlying
disease activity/ can use topical steroids.
Uveitis
Occurs in 0.5-3% IBD.
This may not parallel IBD activity.
75% have axial and/or peripheral arthropathy.
Treatment:
involves systemic or topical steroids/
Infliximab.
A topical mydriatic such as scopolamine (0.25%) or
cyclopentolate (1%) can relieve spasm.
Cataracts
25% of patients receiving 15 mg or more of
prednisone for 1year get posterior subcapsular
cataracts.
Other miscellaneous eye conditions:
Retinal vascular disease with central vein occlusion, and retinal vasculitis
- are rare in Crohn’s.
Subepithelial keratopathy, peripheral corneal ulcers, and corneal infiltrates
-have been
described in several patients with Crohn's disease and ulcerative colitis.
Central serous chorioretinopathy with bullous retinal detachment
- has been reported in one
patient with ulcerative colitis.
Symptoms:
Bilateral, insidious onset and long-lasting
Patients complain of eye pain, blurred vision,
photophobia and headaches
Can progress to secondary glaucoma and loss of
vision
Diagnosis:
Slit lamp: Inflammation in the anterior chamber
with perilimbic edema, cells, and protein.
Corneal clouding and conjunctival injection may
also be seen
Acute episode may be followed by iris atrophy,
lens deposits, and synechiae.
Written by Dr Sebastian Zeki
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