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home - Colon - Diagnostic Pathways for Colonic Disease - AIDS Related Diarrhoea Written by Dr Sebastian Zeki
Methods GMP
Knows the physiology of intestinal absorption, secretion and motility SCE 1
Understands the biochemical processes occurring within the gut
lumen and at mucosal level

Has awareness of the factors controlling these processes – in
particular the neuro-endocrine influences

Understands the range of mechanisms by which diarrhoea can result
from disturbances in each of these processes

Knows the causes of both acute and chronic diarrhoea
Knows the range of investigations appropriate to determining the
cause of the patient’s diarrhoea and is aware of the range of
therapeutic possibilities

Makes a detailed clinical assessment of patients that present with
either acute or chronic diarrhoea

Recognises the potential need for urgent fluid replacement CbD,
Makes appropriate use of microbiology and other relevant laboratories in reaching a diagnosis

Shows ability to interpret results, reach a diagnosis and formulate a
treatment plan

Reacts appropriately to the urgency of the clinical presentation
Always shows sympathy and understanding especially when the
patient is distressed

AIDS Related Diarrhoea

Relevant physical findingsFever: CMV/ MACHepatosplenomegaly: MACRectal tenderness: Proctitis/ CMVPresence of retinitis: CMV Acute or chronic diarrhoea MC&SOva and cystsC diff If CD4 <200uL- AFB smears (cryptosporidium/ cyclospora/ microsporidium)If CD4 <100uL- Trichome stain (Microsporidium)Blood culture if fever or MAC suspected ConsiderUpper GI endoscopy +BxFlexi sig or colonoscopyReassess drug treamtents as cause Negative Assessment of Diarrhoea in AIDS Patients Written by Dr Sebastian Zeki

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