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home - Biliary - Miscellaneous - Porcelain Gallbladder Written by Dr Sebastian Zeki

Porcelain Gallbladder

Written by Dr Sebastian Zeki Histopathology: EpidemiologyThe incidence is 0.1% .M:F= 1:5 .Mean age is 50.15% get gallbladder cancer. Ultrasonographic Types Histopathological Types Corresponds With AXR- Calcifications are in RUQ Porcelain Gallbladder Treatment- Treat with an open cholecystectomy even if asymptomatic (lap difficult as cant grab it easily). Incomplete type — Calcification of the gallbladder wall is milder and there is incomplete exfoliation of the mucosal epithelium.High risk of gallbladder cancer as still have some mucosa Complete type — Gallbladder wall completely replaced by dense fibrosis or calcification. Calcification is so severe that the mucosal epithelium is peeled off. Type III — Irregular clumps of echoes with posterior acoustic shadowing Type II — A biconvex curvilinear echogenic appearance with acoustic shadowing Type I — A hyperechoic semilunar appearance with posterior acoustic shadowing. Often asymptomatic, Some present with biliary type pain.Rarely- firm, nontender mass in the RUQ Pathogenesis Gallbladder wall injury is due to chronic irritation by gallstones.Mucosal precipitation of calcium carbon-ate salts occurs in inflamed tissue. 80% of cancer associated with porcelain GB are adenoca 2 forms:a)Broad muscularis band (plaque-like on radiology)b) Multiple punctate calcifications in the glandular spaces of the mucosa, granular calcifications on radiology. =Intramural calcification of the gallbladder wall.